The duel between Alexander Hamilton and Aaron Burr is perhaps the most famous duel in United States history. There’s a reason the duel between Alexander Hamilton and Aaron Burr took place in New Jersey. Four years before the duel, Hamilton and Burr worked together on one of the most sensational trials of the era. Alexander Hamilton fired first during the duel, but Aaron Burr fired the fatal shot. The night before the duel, he wrote an open letter titled Statement on Impending Duel with Aaron Burr.