With CVI, the blood fails to make a consistent upward climb and pools in the veins. Risk factors for CVI include age, family history, prolonged inactivity, pregnancy, obesity and being quite tall. CVI may also occur in people who have experienced deep vein thrombosis, which is a blood clot in the deep veins of the leg. Chronic venous insufficiency is not life-threatening; if ignored, however, it can lead to serious complications. It’s important for your health that you follow your doctors’ recommendations and make managing CVI part of your daily routine.