The black widow spider, or Latrodectus hesperus, is one of three venomous spiders in found in the United States. While a bite from any spider is unpleasant, a bite from a venomous spider is even more so, but can it kill you? One study on black widow spider toxicity found that in 23,409 cases of exposure to black widow venom, only 1.4 percent of patients had life-threatening symptoms. While it is unlikely that the bite of a black widow will kill you, there is a good chance you’ll experience some unpleasant side effects. The good news is, black widow spiders are not known to attack humans.