Gray whales, bottlenose dolphins, white-tailed deer and Chinese hamsters are at high risk; cats, cows and sheep are at medium risk; and dogs, pigs and horses are at low risk. Precautions are called for with workers around cattle and sheep, which are considered at medium risk of coronavirus infection. Such human-to-animal infection has happened in Utah, as well as in Denmark and the Netherlands, where infected workers on fur ranches infected mink. Infected cats could put other wildlife at risk, especially indigenous predators like the foxes, weasels and mink in Minnesota’s forests and elsewhere. Especially in light of trans-species passage, the development of a safe, effective SARS-CoV-2 vaccine will be a challenge.